In particular, two regions associated with the KALRN (Fig. 4A–C) and WNT7B (Fig. 4D–F) promoters had a difference in DNA methylation between airway epithelial cells isolated from individuals with asthma versus those without asthma of greater than 40% (mean Δβ 0.46 and 0.45 respectively). This evidence concerns the gene WNT7B and asthma.