To explore the characteristics of BCR-ABL1 signals among CML-CP, CML-BP and ALL patients, we assessed and analyzed BCR-ABL1 signals in 243 CML-CP, 17 CML-BP and 52 BCR-ABL1 positive ALL patients using DCDF-FISH. This evidence concerns the gene BCR and chronic myelogenous leukemia, BCR-ABL1 positive.