Conversely, typical single BCR-ABL1 signal pattern was observed in 29.4% (n = 5) of the CML-BP patients, 53.8% (n = 28) of the BCR-ABL1 positive ALL patients and 73.7% (n = 179) of the CML-CP patients (p < 0.001) (Fig. 2b). Here, BCR is linked to acute lymphoblastic leukemia.