Previous studies have revealed that microRNA-10b promotes the metastasis of a variety of tumor cells by regulating Bim, TFAP2C, P16, P21, E-cadherin, CD138, RHOC, RhoC, uPAR, MMP-2, MMP-9, HOXD10, etc 23-29. The gene discussed is TFAP2C; the disease is neoplasm.