GESA showed that apoptosis, the B cell receptor signalling pathway, the calcium signalling pathway, the chemokine signalling pathway, the JAK/STAT signalling pathway, the MAPK signalling pathway, the p53 signalling pathway, pathways in cancer, the T cell receptor signalling pathway, the Toll like receptor signalling pathway, the VEGF signalling pathway, and the Wnt signalling pathway were significantly enriched in the RUNX1 high-expression phenotype. The gene discussed is TP53; the disease is cancer.