RUNX1 and metastatic malignant neoplasm in the lymph nodes: As shown in Figs. 2A–2E, high expression of RUNX1 was significantly associated with gender (p = 0.003), clinical stage (p < 0.001), tissue infiltration (p < 0.001), lymph node metastasis (p = 0.037) and histological grade (p < 0.001).