The studies also revealed that other anti-apoptotic and pro-apoptotic proteins were involved in the apoptosis mechanism of Glab toward Huh7 cells.38 Glab was also able to induce apoptosis in HL60 through up-regulation of the Bax and down-regulation of Bid proteins.37 According to the results, the considerable potential of Glab in inhibition of the proliferation and toxicity of the cancerous cells corresponding to the lung, neuroblastoma, and ovarian carcinoma, could be concluded in this study. This evidence concerns the gene BAX and neuroblastoma.