This association was still significant after adjusting for age, gender, smoking, systolic blood pressure, diastolic blood pressure, dyslipidemia, diabetes duration, EGFR, Hba1c, and cardiovascular disease history (P < 0.0001 for nonfatal stroke and myocardial infarction, P < 0.001 for heart failure, and P < 0.05 for cardiovascular death, respectively). The gene discussed is EGFR; the disease is Stroke.