One of the most interesting observations we made is that simultaneous inhibition of HSPA isoforms by the pan-HSPA inhibitors (VER, JG-98) sensitized NSCLC cells to BTZ (Fig. 6D–I), but not to CDDP (Figs 6A,B and S4A,B) or CPT (Fig. S1C,D). The gene discussed is CASC3; the disease is non-small cell lung carcinoma.