Although our study suggested that TAGLN expressions among the bladder carcinoma cell lines could be dependent on the cell type but not relevant to the extent of neoplasia in vitro, the RT-qPCR analysis of paired human bladder tissues further demonstrated a significantly lower expression of TAGLN mRNA levels in bladder tumors than adjacent normal bladder tissues (Figure 1). This evidence concerns the gene TAGLN and urinary bladder neoplasm.