DPYSL2 and schizophrenia: Because the role of CRMP2 in schizophrenia has been evidenced from the patient studies, we reasoned that the AGE modification of the CRMP2, resulting from schizophrenia-associated genetic aberrations, in neural progenitor cells can contribute to the downstream neurodevelopmental deficits relevant for the schizophrenia pathogenesis, at least in a subset of patients.