STAT3 and breast cancer: In addition, there are numerous other miRNAs that appear to be involved in the suppression of metastasis and invasion of breast cancer in vitro and in vivo; these include the miRNAs miR-497, miR-421, miR-193a, miR-211-5p, miR-335, miR-133a, and miR-124, which are proposed to suppress the expression of SMAD7, MTA1, WT1, SETBP1, EphA4, LASP1, and STAT3, respectively [99,100,101,102,103,104,105].