In the case of COX, PGE2 and MPO in groups witch colitis, the level of above compounds decreased significantly in animals fed with diet supplemented with beta-glucans (CβGl+ and CβGh+ versus CβG−), but only the addition of low molecular weight beta-glucan reduced the level of analyzed compounds to the value detected in the healthy control group (HβG−). This evidence concerns the gene MPO and colitis.