Previous studies showed that increased expression of hypoxia‐inducible factors (HIFs) responded to low oxygen condition.18 Moreover, recent studies on tumour cell lines also found that the expression level of HIF‐1α was positively correlated with GAPLINC expression.18 Hence, we determined the HIF‐1α expression level at the different conditions at both mRNA and protein levels in HUEVC cells. The gene discussed is HIF1A; the disease is neoplasm.