NRG1 and cancer: CASC9 (cancer susceptibility candidate 9), a 1.4 kb cytoplasmic intergenic lncRNA, was obviously overexpressed in human proliferating phase (rapid growth) HA tissues than that in involuting phase (spontaneous regression) HA tissues and normal tissues.95 Further studies indicated that CASC9 accelerated the proliferation, invasion and migration of HA‐derived endothelial cell (HDECs) via negatively regulating miR‐125a‐3p/Nrg1 (neuregulin 1) axis.