Use of these CMKLR1 tracers resulted in distinct target-specific DU4475 tumor uptake with 5.1% IA/g ([68Ga]Ga-DOTA-AHX-CG34), 3.3% IA/g ([68Ga]Ga-DOTA-KCap-CG34) and 6.2% IA/g ([68Ga]Ga-DOTA-ADX-CG34). The gene discussed is CMKLR1; the disease is neoplasm.