However, the recent research has led to the discovery of several CaM mutations in a small group of patients presented mainly with cardiac specific phenotypes, such as long QT syndrome (LQTS), idiopathic ventricular fibrillation (IVF), and catecholaminergic polymorphic ventricular tachycardia (CPVT). The gene discussed is CALM1; the disease is catecholaminergic polymorphic ventricular tachycardia.