According to data from adult adolescent clinics of the country's universities during 2015-2016, the proportion of people with type 1 diabetes was 11.4%, type 2 diabetes, 85.5% and other types of diabetes was 1.3%; despite having access to drug and coating insulin use in Iran, the control of this disease and its causes has proved to be difficult14. Here, INS is linked to type 1 diabetes mellitus.