With regard to mRNA expression, RelB mRNA levels were strongly increased in cancerous specimens compared to tumor-adjacent non-neoplastic tissues (Fig. 3b, P = 0.009), while mRNA levels of NF-κB2, Bcl3 and NIK did not differ between neoplastic and non-neoplastic tissues (Fig. 3). The gene discussed is RELB; the disease is neoplasm.