The Western blot (WB) results also showed that CCNB1 (p < 0.001) and N-cadherin (p < 0.001) were overexpressed in the invasive pituitary adenomas compared to the non-invasive pituitary adenomas and that E-cadherin (p < 0.001) expression was significantly decreased (Fig. 2b, c). Here, CCNB1 is linked to pituitary gland adenoma.