CYP1B1 and nasopharyngeal carcinoma: The genes that were significantly downregulated in the NPC samples (Fig 4A-1) as compared to the gastric samples that are involved in migration, invasion, and epithelial differentiation had predicted upstream regulators CBX5, CYP1B1, ETS2, TGFB1, BMP4, SYVN1, IFNG, and SMARCA4.