Asimismo, se ha descrito que la leptina induce la migración celular en dos líneas de cáncer de mama: la MDA-MB-231, con fenotipo invasivo, y la línea no invasiva MCF7 (Juárez-Cruz JC, García- Rodríguez E, Castañeda-Saucedo E, Mendoza-Catalán MA, Villegas S, et al. Leptin induces cell migration, gelatinases secretion and invasion in a FAK-Src dependent pathway in breast cancer cell. The gene discussed is PTK2; the disease is breast carcinoma.