3 Grossmann Grossmann M M Ray Ray A A Nkhata Nkhata K K Malakhov Malakhov D D Regozina Regozina O O Dogan Dogan S S Obesity and breast cancer: Status of leptin and adiponectin in pathological processes Obesity and breast cancer: Status of leptin and adiponectin in pathological processes Cancer Metastasis Rev Cancer Metastasis Rev 2010 2010 29 29 641 641 653 653 10.1007/s10555-010-9252-1 10.1007/s10555-010-9252-1 20821253 20821253. The gene discussed is LEP; the disease is obesity due to melanocortin 4 receptor deficiency.