Individuals whose biopsies demonstrated definite NASH, compared with those with NAFL, were older (mean [SD], 49 [11] vs 45 [11] years; P = .007), were more likely to have diabetes (115 of 276 [41.7%] vs 18 of 86 [20.9%]; P < .001) and metabolic syndrome (109 of 142 [76.8%] vs 21 of 38 [55.3%]; P = .03), and had higher liver enzyme levels (eg, mean [SD] ALT, 87 [61] vs 53 [29] U/L [to convert to microkatals per liter, multiply by 0.0167]; P = .002) (Table 1). This evidence concerns the gene GPT and metabolic syndrome.