Cognitive problems including cognitive decline and psychomotor retardation have been reported in all but 5 genetic disorders, MYC/DYT‐SGCE, MYC/DYT‐KCTD17, mUDP7 (based on loss of SGCE‐gene), DYT‐ANO3, and the hyperekplexias. The gene discussed is ANO3; the disease is Mental deterioration.