MFSD2A and hepatocellular carcinoma: The serum MFSD2A level in HCC patients was significantly lower than that in in HCs (P = 0.0079) and HBV-infected controls (P = 0.0430), resulting in an AUC of 0.718 (0.567–0.869), a sensitivity of 76.3%, and a specificity of 66.7% with an optimal cut-off value of 35.23 ng/ml, as shown in Figure 2H, 2I.