IMMT and cancer: An et al. reported that a novel mitochondrial protein CHCM1/CHCHD6 directly interacts with IMMT and coordinately maintains the structural integrity of the mitochondrial cristae.24 Furthermore, they demonstrated that CHCM1/CHCHD6 knockdown affected cancer cell growth and enhanced chemosensitivity to anticancer drugs, whereas the increased exogenous expression of these markers desensitized cancer cells to these agents.