T helper 1 (Th1) cells play a central role in the host defense by inducing the production of IFNγ, which potentiates the nitric oxide- (NO-) dependent killing activity of macrophages, while IL-2 is an essential cytokine for the development and proliferation of Th1 and CD8+ T cells, and Th17 cell secretes IL-17 and IL-23 that plays inflammatory response of TB [41, 42, 47, 53, 59]. This evidence concerns the gene IL17A and tuberculosis.