A recent study has shown that two intronic variants rs11066782 and rs11613718 in KCTD10 or potassium channel tetramerisation domain-containing 10 gene were associated with high-density lipoprotein cholesterol (HDL-C) concentrations and with coronary heart disease (CHD) risk [27], while rs2338104 in the KCTD10 gene located in chromosome 12q24 was associated with AMD development [28]. The gene discussed is KCTD10; the disease is age-related macular degeneration.