A high E/E'sr ratio (per 10 cm) was significantly associated with overall mortality in the unadjusted model (HR, 1.191; 95% confidence interval (CI), 1.090−1.301; p < 0.001), in the age- and sex-adjusted model (HR, 1.185; 95% CI, 1.074−1.308; p = 0.001), and in the multivariable model adjusted for age, sex, dialysis vintage, DM, coronary artery disease, cerebrovascular disease, BMI, systolic blood pressure, ABI < 0.95, baPWV, cardiothoracic radio, AoAC, albumin, triglycerides, total cholesterol, hemoglobin, creatinine, calcium-phosphorous product, and hs-CRP. The gene discussed is ALB; the disease is diabetes mellitus.