ACE and diabetes mellitus: Patients belonging to the 3rd tertile of the E/E'sr ratio had higher prevalence of DM and coronary artery disease, higher cardiothoracic ratio, higher AoAC, lower serum creatinine, higher prevalence of ACE inhibitors or ARB and β-blocker use, higher LAVI, higher LVMI, lower LVEF, higher E/E' ratio, higher E/A ratio, lower E' wave, lower E'sr, and less negative GLS compared to patients in the 1st tertile of the E/E'sr ratio (Table 1).