As shown in Table 4, the addition of the E/E' ratio to the basic model (comprises age, sex, dialysis vintage, DM, coronary artery disease, cerebrovascular disease, BMI, systolic blood pressure, ABI < 0.95, baPWV, cardiothoracic ratio, AoAC, album, triglycerides, total cholesterol, hemoglobin, creatinine, calcium-phosphorous product, hs-CRP, and the use of ACE inhibitors or ARBs, β-blockers, and statins) did not significantly improve the prediction for overall mortality, CV mortality, and MACE. The gene discussed is ACE; the disease is diabetes mellitus.