Axl overexpression was significantly correlated with poor prognosis (2.03-fold increase in mortality in all solid tumor patients); in a subgroup analysis of different cancer types, Axl overexpression was correlated with shorter overall survival in a few tumors, including HCC (combined HR of 1.89 (95% CI 1.37–2.60, p < 0.001)) [113]. This evidence concerns the gene AXL and hepatocellular carcinoma.