The measurement of the soluble levels of Gas6 and its receptors (e.g., sAxl and sMERTK [102]) could furthermore be the basis of providing an easy and accurate measurement of hepatic fibrosis progression, since numerous other targets for antifibrotic agents are difficult to be analyzed or to enter early-phase clinical studies due to the lack of sensitive markers to follow the effects [90]. The gene discussed is GAS6; the disease is Hepatic fibrosis.