FGF21 and Obesity: Our present study revealed that the FGF21 value has correlation with obesity and dyslipidemia parameters such as BMI, WC, body fat mass, and serum TG, HDL-C, and LDL-C levels in the univariate linear regression analysis in T2DM patients and that body fat mass and serum log-TG levels still had positive association with serum FGF21 level even after performing multivariate linear regression analysis, indicating the phenomenon of FGF21 resistance exists in T2DM populations.