Specifically, based on the results of our IHC analysis of TLR3 protein in 194 NSCLC cohort revealing one-third of the case study (37.6%) with a percentage of TLR3 positive tumor cells ≥50%, we analyzed NSCLC cohort in KM-Plotter database dividing cases into tertiles, according to levels of TLR3 mRNA expression, and the highest quantile was considered to be TLR3-positive similarly to what defined for IHC. The gene discussed is TLR3; the disease is neoplasm.