ESR1 and cancer: Comparison between ER positive and ER negative cancers as measured by PCR, validated the results, demonstrating a logFC of 0.87 for let-7b-5p (p = 0.029), logFC − 1.57 for miR-146a-5p (p = 0.00014), logFC − 0.99 for miR-3182 (p = 0.028), logFC 0.88 for let-7c (p = 0.029) and a logFC of − 1.64 for miR-155-5p (p = 0.00012).