This was co-correlated with general decreases in multiple glycolytic and PPP enzymes in the NSCLC mesenchymal state, including phosphofructokinase (PFKFB2,3), fructose-1,6-biphosphatase (FBP1), hexokinase-2 (HK2), and glycerol 6-phosphate dehydrogenase (G6PD) at the RNA (Figure 1D) and protein levels (data not shown). This evidence concerns the gene HK2 and non-small cell lung carcinoma.