Wang and collaborators, going deep inside into the role of this lncRNA in the pathogenesis of epilepsy, showed that UCA1 is able to induce or even aggravate epilepsy in a pilocarpine-induced rat model through the interaction with NF-kB and that UCA1 expression in the peripheral blood of epilepsy rats is positively correlated with that in brain tissue [56]. This evidence concerns the gene NFKB1 and epilepsy.