Moreover, growing evidence has proven TIM-1 to be a cellular receptor which facilitates viral infection, and existent in a number of various viruses, including Ebola virus (EBOV), Marburg virus (MARV), Lassa virus, HAV, Hepatitis C virus (HCV), JEV, and DENV [39,40,41,42,43,44,45,46]. This evidence concerns the gene HAVCR1 and viral infectious disease.