NFKB1 and Familial prostate cancer: Curcumin has been shown to inhibit proliferation and invasion and induce apoptosis of prostate cancer cells in vitro and in vivo through interfering with various signaling pathways including mitogen-activated protein kinase (MAPK), epidermal growth factor receptor (EGFR), and nuclear factor κ (NFκB) [7,8,9].