In our cohort, pathogenic variants were also detected in a number of other deafness genes, including KCNQ4, POU3F4, MYO7A, TMPRSS3, EYA1, TECTA, MITF, POU4F3, PJVK, COL4A5, WFS1, GATA3, SIX5, USH2A, OTOG, PAX3, MYO6, ATP6V1B2, SOX10, PTPRQ, EPS8L2, and EDNRB, as shown in Table 6. The gene discussed is COL4A5; the disease is deafness.