Whereas tumor‐suppressive functions of LRIG1 (Mao et al., 2018) and LRIG3 (Guo et al., 2015) have been reported in malignant glioma, LRIG2 seems to act more as an oncoprotein (Holmlund et al., 2009; Rondahl et al., 2013; Xiao et al., 2014). This evidence concerns the gene LRIG1 and neoplasm.