EGF and cancer: THBS1 attracted our attention because of its EGF‐like motifs (Carlson et al., 2008), its function in the modulation of the ECM, angiogenesis, and its implication in SCC and other types of cancer (Donnini et al., 2004; Huang et al., 2017; Qian et al., 1997; Tan and Lawler, 2009).