MAPK8 and myocardial infarction: In mice, inhibition of autophagy by bafilomycin, or genetic beclin heterozygosity as well as ATG5 knockout impairs angiogenesis post myocardial infarction, whereas the angiogenic factor AGGF1 enhances therapeutic angiogenesis through JNK-mediated stimulation of endothelial autophagy (Lu et al., 2016).