Eplerenone is an aldosterone receptor antagonist that has been introduced for the management of hypertention,14, 15 also proven to be effective in reducing cardiovascular diseases secondary to hypertension,16, 17 this drug has also been shown to reduce mortality in patients with heart failure after myocardial infarction.18, 19. The gene discussed is NR3C2; the disease is myocardial infarction.