Noting sporadic and C9orf72RE ALS patients, but not SOD1 mutation patients, typically exhibit shared TDP‐43 pathology 16 we have therefore, for the first time, compared the regional expression of AMPARs in sALS patients together with patients with SOD1 (I114T) and C9orf72RE mutations. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.