FMR1 and autism: We considered seven ASD-associated gene sets: (i) FMRP RNA binding targets (11), (ii) RBFOX (RBFOX1/2/3) RNA binding targets (10), (iii) RBFOX splicing targets (10), (iv) ASD-associated genes [Simons Foundation Autism Research Initiative (SFARI)], (v) DD-associated genes (20), (vi) genes encoding postsynaptic density proteins (21), and (vii) genes involved in the synaptome (21).