Additionally, although A549 and A427 had previously shown different susceptibility to several chemotherapies and other anti-cancer agents (Lu & Arthur, 1992; Odonkor & Achilefu, 2009; Luque et al., 2012; Garon et al., 2014), here we found that they shared similar features of cell death when treated with I-CRP. This evidence concerns the gene CRP and cancer.