Therefore, to evaluate if this also occurs in NSCLC cell lines, we pre-incubated A549 and A427 cells with a pan caspase-inhibitor (QVD) before treating cells with I-CRP or etoposide, an apoptosis inductor (Montecucco, Zanetta & Biamonti, 2015) used as a positive control, and analyzed cell death. The gene discussed is CRP; the disease is non-small cell lung carcinoma.