IFNL1 and Autoimmunity: Activation of NF‐κB signalling became more significant when RAW264.7 cells stimulated with both IL‐29 and LPS than IL‐29 stimulation alone, suggesting that LPS may regulate the effect of IL‐29 and the role of IL‐29.11 In RA patients, serum IL‐29 levels were reduced after the treatment with DMARDs.32 Collectively, these data suggested that IL‐29 is also controlled in autoimmunity.