Administration of IL‐29 in KCs also promoted TLR3 expression.18 IL‐29 treatment significantly enhanced the expression of IFN‐β induced by herpes simplex virus type 1 (HSV‐1) and protected KCs from HSV‐1 attack.18 Therefore, IL‐29 could regulate TLR3 and IFN‐β expression in KCs and then play a part in antiviral activity. Here, TLR3 is linked to dry eye syndrome.