IL1B and congenital rubella syndrome: The results showed that pro-inflammatory cytokines, IL-1β and IL-6, were significantly up-regulated in the CRS group (stress effect: IL-1β, F(1,16) = 8.8, p < 0.02; IL-6, F(1,16) = 10.4, p < 0.02), and that this increase was blocked by chronic Oxo treatment (treatment effect: IL-1β, F(1,16) = 4.0, p = 0.8; IL-6, F(1,16) = 3.2, p = 0.11) (stress × treatment effect: IL-1β, F(1,16) = 2.26, p = 0.17; IL-6, F(1,16) = 17.26, p < 0.01) (Fig. 5A,B).