To quantitatively compare the stromal sources of bone NGF in human disease, MM or MGUS patient-derived BM stromal cells (BMSC) and marrow adipose tissue (MAT) were compared to the highly-secretory BMSC cell line HS-5 for expression of NGF and tumour supportive factors IL6 and TNFA by qPCR. This evidence concerns the gene IL6 and Miyoshi myopathy.