AIF1 and neoplasm: In tumour-bearing mice, we detected significant activation of GFAP+ astrocytes (Fig. 2c,d) and Iba1+ microglia (Fig. 2e,f) in the spinal cords of KaLwRij mice at the vertebral T8, which in mice corresponds to spinal cord segment T10, suggesting a response to MM in the hips and hind legs36.