Tumor size >2 cm (P = .033), histological grade III (P = .012), lymph node-positive (P = .024), TNM stage III (P = .005), HIF-1α-positive expression (P < .001), and c-myc-positive expression (P = .003) were the risk factors of postoperative survival in TNBC patients. The gene discussed is HIF1A; the disease is neoplasm.