NF1 and scoliosis: NF-1 occurs in approximately one in 3500 individuals.[1] A total of 10% to 25% of NF-1 will present with bone malformation, which includes scoliosis, congenital arch and pseudo-joint formation, bone cyst, thinning of cortical bone, and subperiosteal bone hyperplasia.[2] X-rays often show trabecula disruption, cortical distortion, sclerotic zone, bone hyperplasia, and soft tissue swelling.