CCL2 and type 1 diabetes mellitus: Other markers of inflammation that were found to be independently associated with eGFR decline include circulating interleukin (IL)-6 [106] and C-reactive protein [107] and urinary monocyte chemotactic protein-1 (MCP-1) [108], in patients with T2D, and multiple urinary inflammatory markers (IL-6, IL-8, MCP-1, interferon-γ-inducible protein, and macrophage inflammatory protein-1δ) in patients with T1D [109].