At present, many studies have already indicated that AURKB is a promising therapeutic target in various cancers, such as non-small cell lung cancer (NSCLC) (Bertran-Alamillo et al., 2019), gastric cancer (GC) (He et al., 2019), leukemia (He et al., 2016), prostate cancer (PC) (Addepalli et al., 2010), and breast cancer (Han et al., 2017). Here, AURKB is linked to Familial prostate cancer.