CELF4 and cancer: In the red module, we identified two key up-regulated RBPs (TDRD1 and TDRD9) and one key down-regulated RBP, CELF4. These results suggest that dysregulated RBPs play a key role in the regulation of the development of the CHOL and KICH M-stage, which may provide a new perspective for potential prognostic biomarkers and therapeutic targets for patients with cancers at M stages in two cancer types CHOL and KICH.